Why 1.73 m2

Race: There is increasing concern that the adjustment for ethnicity does not reflect the wide diversity within individuals of black ethnicity, with the adjustment based on outdated and unfounded biological assumptions for differences between ethnic groups at the expense of better understanding of social and ancestral determinants. In the NICE chronic kidney disease CKD guideline the recommendation to adjust for ethnicity, present in the version, has been removed. Further evidence is needed and there is concern by professionals and patients that adjustment may be a source of inaccuracy and potential inequity.

Not so good near normal: The equations used for estimating eGFR tend to underestimate normal or near-normal function therefore slightly low values i. In this situation repeat testing, looking for a progressive decline in renal function over time, or measurement of cystatin C a different biomarker of kidney function may be useful. Additional indicators or renal disease should also be sought in these patients — e.

Note, however, that a significant e. Values can differ between laboratories. Creatinine measurements can differ significantly between laboratories depending on the methods used to measure it.

Furthermore, different laboratories may use a different formula to calculate the eGFR further complicating comparison of eGFR measurements obtained from different laboratories. Creatinine level must be stable: eGFR calculations assume that the level of creatinine in the blood is stable over days or longer i. It is therefore not valid in patients with acute kidney injury or in patients receiving dialysis, for example.

Patient information The level of creatinine in the blood is a useful guide to kidney function or the glomerular filtration rate GFR. About CKD stages. You can also search for this author in PubMed Google Scholar. Correspondence to Pouria Mousapour. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

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